Police are appealing for witnesses after the theft from a lorry near Blythe Bridge.
Thieves struck between 8.45pm on Tuesday 1 April and 5.45am on Wednesday 2 April while the lorry was parked in a layby on the westbound carriageway of the A50, just before the turning for Blythe Bridge.
They stole a rear wheel with the wheel nuts, worth around £650, and around 420 litres of diesel from the fuel tank, worth around £550.
Anyone who witnessed the theft, or who has information on who is responsible, is asked to contact PC Simon Hollis at Staffordshire Police on 101, quoting incident number 71 of April 2. Alternatively, they can contact independent charity Crimestoppers, anonymously, on 0800 555 111.